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ITOR's Integration with GHS & the Cancer Centers of the Carolinas

In the above video, Dr. Gluck talks about the benefits to patients when Greenville Health System and Cancer Centers of the Carolinas merge to provide better cancer treatments to South Carolina cancer patients.


  • Greenville Health System
  • The Cancer Center of Greenville Health System
  • Cancer Centers of the Carolinas

Greenville Health System

Vision: Transform health care for the benefit of the people and communities we serve.

Mission: Heal compassionately. Teach innovatively. Improve constantly.

Core Values: Our core values are compassion, respect, caring, honesty, integrity, and trust. We live our values through open communication, forward thinking, creativity, continually striving to improve, responsiveness, a willingness to change, education, research, and clinical quality.

As South Carolina’s largest healthcare system with over 10,000 employees, the Greenville Health System has been awarded university medical center status with a strong tradition of patient care, research, and academia.

Cited as a US News and World Report top 50 Institution in 2009 and 2010, GHS brings a large contingent of virtually all relevant surgical oncology subspecialties as well as a competitive pediatric oncology program.

Other supportive oncology programs within the Greenville Health System – such as interventional radiology, radioimmunoconjugate therapy, and dedicated sub-specialty pathology expertise – reinforces the strength and comprehensiveness of GHS’s care of cancer patients, while the system concurrently supports the vision and diverse needs of the Institute for Translational Oncology Research (ITOR) of Greenville Health System (GHS).

About GHS

Greenville Health System is composed of 5 campuses providing integrated healthcare to communities across Upstate South Carolina and the I-85 corridor. GHS is accredited by the Joint Commission of Accreditation of Hospital Organizations (JCAHO) and is committed to medical excellence through advanced care, innovative training and research, and strategic partnerships.

  • U.S. News ranked Greenville Memorial Hospital among the nation's top 50 hospitals for care provided in five specialty areas:
    • Diabetes and endocrine disorders
    • Digestive problems
    • Heart and heart surgery
    • Neurology and neurosurgery
    • Orthopaedics
  • In 2010, GHS received National Accreditation from the Association for the Accreditation of Human Research Protection Programs (AAHRPP). At any given time, approximately 500 clinical trials are occurring at GHS.
  • GHS has 7 ACGME accredited medical residency programs and five fellowship programs, and is the training site for over 50 third & fourth year medical students from the University of South Carolina School of Medicine and is soon to be a site of an expanded 4 year medical school campus.
  • The GHS Chest Pain Center is ranked among the top two percent in the nation for outstanding performance and efficiency.
  • The GHS Breast Health Program was the first in the region to receive full accreditation from the National Accreditation Program for Breast Centers (NAPBC).

The Office of Philanthropy & Partnership is the philanthropic arm of GHS. In addition to building philanthropic support for programs throughout the hospital system, the Office of Philanthropy & Partnership advocates several unique philanthropy initiatives that contribute to cancer research.


Cancer Center of Greenville Health System

A Message from the Office of the Director of the GHS Cancer Center:

The Cancer Center of GHS is a large, regional referral center with comprehensive offerings for adult and childhood malignancies and hematologic disorders. As part of an academic medical center, it offers a broad spectrum of state-of-the-art cancer services while serving as a leading center for cancer research as well as undergraduate and post-graduate medical education. Complementing the diverse treatment options of our NCI-designated CCOP has been the evolving phase one program initiated in 2004. This effort has expanded to include biorepository, cancer proteomics and genomics capabilities, while forging unique university and biotechnology partnerships. These efforts have culminated in the creation of the Institute for Translational Oncology Research as a major pillar of cancer research at GHS. This institute will strengthen patient options and enhance treatment availability to progressively solidify the GHS Cancer Center as a destination for patients and their families.

Larry Gluck, M.D.
Cancer Center of Greenville Health System

Clinical Trials

The GHS Cancer Center performs more than 100 clinical trials to give patients access to new or alternative therapies. Many of the trials are conducted through the ITOR Clinical Research Unit (CRU) as well as through the Greenville Community Clinical Oncology Program (CCOP) of Cancer Centers of the Carolinas.

Oncology Research

Basic research of cell biology, molecular biology, and development biology is conducted through Clemson University’s onsite Biomedical Institute to discover new approaches to cancer prevention and treatment. Clemson University’s Biomedical Institute is Upstate South Carolina's only basic science cancer research facility.

Oncology Rehabilitation

The GHS Cancer Center also offers a unique Oncology Rehabilitation Program, called Moving On, to assist patients with addressing the side effects of cancer and cancer treatments. The program helps decrease fatigue, increase strength, and improve quality of life.

Treatment Collaboration

In conjunction with Cancer Centers of the Carolinas, the GHS Cancer Center provides unique programs focused on advanced treatment and comprehensive care. The Oncology Multidisciplinary Center (MDC) was developed for disease specific, rapid comprehensive cancer consultation. The dedicated centers each meet one to two times weekly and include thoracic, breast, gastrointestinal, genitourinary, neuro oncology, and melanoma/sarcoma. The MDC is physically juxtaposed to the ITOR Clinical Research Unit, a propitious configuration for professional interchange, patient evaluation and trial accrual.

The Cancer Center's commitment to providing patients with exceptional care earned the facility the prestigious 2009 American College of Surgeons' Commission on Cancer (CoC) Outstanding Achievement Award as well as a 3-year accreditation with commendation from the CoC for outstanding adherence to standards of excellence in cancer care.

Cancer Centers of the Carolinas

In 2002, the oncologists of Cancer Centers of the Carolinas (CCC) and the Greenville Health System entered a collaboration to unite South Carolina’s largest physician oncology group with the state’s largest hospital provider to create a premiere Cancer Center for the Southeast United States.

The 25 oncologists at CCC include medical oncology, radiation oncology and gynecologic oncology, and carry a nationally claimed reputation for excellence in cancer research under the Greenville CCOP. US Oncology provides management expertise for CCC and brings nationwide experience with over 1000 oncologists, as well as a Phase 1 network.

CCC is the largest referral source for the Institute for Translational Oncology Research with Jeff Edenfield, serving as medical director of ITOR of GHS.

Cancer Centers of the Carolinas – Commitment to Translational Research:

Cancer care in the last decade has made many advances through clinical research via clinical trials or research studies. Clinical trials have resulted in new treatments and prevention options for cancer care. The oncologists of CCC are committed to ongoing studies of new, leading-edge therapies and research for new cancer treatments. CCC oncologists study and adopt the latest treatments that offer more hope for effective treatment of numerous cancers.

The National Cancer Institute has awarded Cancer Centers of the Carolinas a research grant and designated CCC as a Community Clinical Oncology Program (CCOP). Typically, these grants are awarded to hospital-based research institutes. As one of only 63 such research centers in the country to be awarded this grant, CCC provides patients with state-of-the-art cancer care closer to home. In 2008, CCC was the recipient of the prestigious American Society of Clinical Oncology Trials award.

Patients may participate in clinical trials from seven research bases:

CCC also participates in clinical trials through independent pharmaceutical companies as well as through US Oncology. The affiliation with US Oncology allows CCC to pool the knowledge and experience of a network of over 1,000 cancer specialists throughout the nation. This network constantly studies the best possible treatments for every type of adult cancer.